The condition is more likely to occur when you first start a medicine or increase the dose. Serotonin syndrome can occur if you are taking medications, particularly antidepressants, that affect the body's level of serotonin. The greatest risk of serotonin syndrome occurs if you are taking two or more drugs and/or supplements together that influence serotonin.
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Other prescription and over-the-counter drugs that can raise serotonin levels alone or in combination to cause serotonin syndrome include:
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The most commonly prescribed class of antidepressants, which work by increasing serotonin, are the serotonin reuptake inhibitors (SSRIs).These include Celexa ( citalopram ), Lexapro ( escitalopram ), Paxil (paroxetine), Prozac ( fluoxetine ), and Zoloft ( sertraline ).
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Symptoms may include:. Serotonin syndrome symptoms often begin within hours of taking a new medication that affects serotonin levels or excessively increasing the dose of one you are already taking.
If you experience any of these symptoms, you or someone with you should seek medical attention immediay:. In severe cases, serotonin syndrome can be life-threatening.
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Serotonin is a chemical produced by the body that enables brain cells and other nervous system cells to communicate with one another. Too little serotonin in the brain is thought to play a role in depression. Too much, however, can lead to excessive nerve cell activity, causing a potentially deadly collection of symptoms known as serotonin syndrome.Imitrex serotonin syndrome