Check for drug interactions and learn what drug combinations to avoid with the RxList drug interaction checker tool.
An interaction can result when there is an increase or decrease in:. There are several mechanisms by which drugs interact with other drugs, food, and other substances.
There are various potential mechanisms through which the absorption of drugs can be reduced. Most drugs are absorbed into the blood and then travel to their site of action. Most drug interactions that are due to altered absorption occur in the intestine. These mechanisms include:.
The absorption of some drugs is increased by food. Conversely, when a drug's absorption is reduced by food, the drug is taken on an empty stomach.
This tool may not cover all possible drug interactions. Please check with a physician if you have health questions or concerns. Although we attempt to provide.
Contraindicated: Never use this combination of drugs because of high risk for dangerous interaction.
Mild: Interaction is unlikely, minor, or nonsignificant.
Q: How do you classify the seriousness of an interaction?
Serious: Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed.
Q: Why is my interaction listed multiple times?
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Q: Why can’t I enter my medication?
Q: What is an interaction?
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Check for multi-drug interactions including alcohol, food, supplements & diseases. Includes detailed reports for both patients and health professionals.
Drug interactions occurs when the effect of a particular drug is altered when it is taken with another drug, or with food.
To view content sources and attributions, please refer to our editorial policy. Data sources include Micromedex (updated Sep 2nd, 2016), Cerner Multum (updated Sep 5th, 2016), Wolters Kluwer (updated Aug 8th, 2016) and others. provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment.
The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Available for Android and iOS devices.
The Drug Interaction Checker will also display any interactions between your chosen drug(s) and food. The Drug Interaction Checker explains the mechanism of each drug interaction, the level of significance of the interaction (major, moderate or minor), and in certain cases, can provide the recommended course of action to manage the interaction.
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Drug Interaction Checker. Use the search field above to look up prescription or OTC drugs, and herbal supplements; Add a full drug regimen and view.
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Check for potential interactions between drugs with this drug interaction tool.